Interpreting High AST/ALT Without Liver Damage

Discussion on labs, biomarkers, interpreting results, and maintaining long-term health.


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TropicStrength
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Joined: Mon Dec 08, 2025 3:24 am

Interpreting High AST/ALT Without Liver Damage

Post by TropicStrength »

Got my labs back. AST is 85 and ALT is 70. I trained heavy legs 24 hours prior. Is this likely muscle damage rather than liver stress?
AndeanLifter
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Joined: Mon Dec 08, 2025 3:24 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by AndeanLifter »

Almost certainly. Check your GGT. If GGT is low, the enzymes are coming from skeletal muscle breakdown, not liver hepatocytes.
MedellinMuscle
Posts: 13
Joined: Mon Dec 08, 2025 3:25 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by MedellinMuscle »

Check your Creatine Kinase (CK) as well. If that is elevated, it confirms the muscular origin of the AST/ALT.
CaliFlex
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Joined: Mon Dec 08, 2025 3:25 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by CaliFlex »

I had a doc freak out over this once. I told him I deadlifted 500lbs the day before and he just stared at me blankly.
LatinoBulk
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Joined: Mon Dec 08, 2025 3:26 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by LatinoBulk »

Always take at least 5-7 days off training before blood work if you want "clean" liver markers. Muscle micro-tears leak enzymes.
TropicStrength
Posts: 1
Joined: Mon Dec 08, 2025 3:24 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by TropicStrength »

Good tip. My CK was actually 1200, so that explains a lot.
AndeanLifter
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Joined: Mon Dec 08, 2025 3:24 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by AndeanLifter »

1200 is actually quite normal for a heavy lifter. I've seen guys hit 3000 after a high-volume session.
MedellinMuscle
Posts: 13
Joined: Mon Dec 08, 2025 3:25 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by MedellinMuscle »

Did you look at your Bilirubin levels? If those are normal, your liver is likely fine.
TropicStrength
Posts: 1
Joined: Mon Dec 08, 2025 3:24 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by TropicStrength »

Bilirubin was 0.8 mg/dL. So well within range.
CaliFlex
Posts: 10
Joined: Mon Dec 08, 2025 3:25 am

Re: Interpreting High AST/ALT Without Liver Damage

Post by CaliFlex »

You are solid then. Just typical trainee bloods.
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