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Mechanism of Action: SARM Binding Affinity Studies

Posted: Tue Sep 03, 2024 5:32 pm
by MedellinMuscle
SARMs are often marketed as side-effect free, but their binding affinity to androgen receptors varies wildly. Let's look at the latest competitive binding assays.

Re: Missing Blood Markers

Posted: Tue Sep 03, 2024 6:12 pm
by MedellinMuscle
Everyone checks Test and E2, but almost no one checks Pregnenolone or DHEA-S. These are the precursors that crash first.

Re: Missing Blood Markers

Posted: Tue Sep 03, 2024 7:32 pm
by Peterdyday
Cystatin-C is another big one. Creatinine is useless for us because our muscle mass and high protein intake skew the results.

Re: Missing Blood Markers

Posted: Tue Sep 03, 2024 9:42 pm
by CoachIronwell
Agreed on Cystatin-C. My eGFR always looks like I have Stage 2 kidney disease on a standard panel, but Cystatin-C shows I am perfectly healthy.