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Cardiovascular Impact of Long-Term AAS Use
Posted: Sun Sep 08, 2024 9:09 am
by MedellinMuscle
Long-term AAS use is known to cause left ventricular hypertrophy. At what dosage and duration do these changes become irreversible according to current data?
Re: Myostatin Inhibitors
Posted: Sun Sep 08, 2024 9:39 am
by Peterdyday
YK-11 is often marketed as a SARM, but it’s actually a steroidal myostatin inhibitor. The follistatin expression it induces is where the real magic happens.
Re: Myostatin Inhibitors
Posted: Sun Sep 08, 2024 10:39 am
by Herbertysnilm
Problem is the half-life. Most people dose it once a day when the pharmacokinetics suggest it needs at least twice-daily administration.
Re: Myostatin Inhibitors
Posted: Sun Sep 08, 2024 11:39 am
by MedellinMuscle
Has anyone looked into the "Belgian Blue" cattle gene? Inhibiting myostatin leads to massive muscle mass but terrible tendon integrity.
Re: Myostatin Inhibitors
Posted: Sun Sep 08, 2024 1:19 pm
by CoachIronwell
That’s the hidden danger. Muscle growth outpaces tendon strengthening, leading to catastrophic ruptures. Be careful with heavy triples on YK.
Re: Myostatin Inhibitors
Posted: Sun Sep 08, 2024 3:16 pm
by SlavPower
Is there any natural way to blunt myostatin? I heard Epicatechin from dark chocolate has some valid human data behind it.