Liver Toxicity Markers: AST/ALT vs GGT in Athletes

[MedellinMuscle]

AST and ALT are general markers, but GGT is often more specific to cholestasis. Why do we rarely see GGT discussed in "liver support" threads?

[CoachIronwell]

The primary takeaway from the recent meta-analysis is that Clomid is becoming secondary to Enclomiphene due to the isomer profile.

[MedellinMuscle]

Enclomiphene definitely shows better LH/FSH response with fewer of the emotional side effects associated with the zuclomiphene isomer.

[Herbertysnilm]

We also need to consider HCG timing. Using it during the cycle prevents Leydig cell atrophy, making the restart much smoother.

[SlavPower]

Exactly. Waiting until 3 weeks post-long ester to start HCG is a dated protocol. The "Power PCT" model is far more evidence-based.

[Peterdyday]

Does the meta-analysis mention Triptorelin? I know it was hyped as a one-shot restart, but the data on pituitary desensitization is scary.

[CoachIronwell]

Triptorelin is high risk. The study suggests it should only be used as a last resort under strict medical supervision.

[MedellinMuscle]

What about the duration? Most PCTs are 4 weeks, but the data suggests 6-8 weeks is better for long-term retention of gains.

[Herbertysnilm]

Agreed. Pituitary signaling returns fast, but testicular volume and function take longer to normalize.