Mechanism of Action: SARM Binding Affinity Studies

[MedellinMuscle]

SARMs are often marketed as side-effect free, but their binding affinity to androgen receptors varies wildly. Let's look at the latest competitive binding assays.

[MedellinMuscle]

Everyone checks Test and E2, but almost no one checks Pregnenolone or DHEA-S. These are the precursors that crash first.

[Peterdyday]

Cystatin-C is another big one. Creatinine is useless for us because our muscle mass and high protein intake skew the results.

[CoachIronwell]

Agreed on Cystatin-C. My eGFR always looks like I have Stage 2 kidney disease on a standard panel, but Cystatin-C shows I am perfectly healthy.