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mTOR Pathway
Posted: Sun Sep 01, 2024 12:10 pm
by SlavPower
Starting a deep dive into leucine thresholds...
Re: Cardio Impact
Posted: Sun Sep 01, 2024 1:10 pm
by Herbertysnilm
Left Ventricular Hypertrophy (LVH) is almost inevitable for long term heavy users. The question is management of blood pressure.
Re: Cardiovascular Impact
Posted: Sun Sep 01, 2024 1:10 pm
by Herbertysnilm
The heart is a muscle. If you give it orals and heavy gear for a decade, Left Ventricular Hypertrophy (LVH) is a statistical certainty.
Re: mTOR Pathway
Posted: Sun Sep 01, 2024 1:14 pm
by MedellinMuscle
The 3g threshold is often cited, but bodyweight matters.
Re: Cardio Impact
Posted: Sun Sep 01, 2024 2:10 pm
by MedellinMuscle
Telmisartan is the gold standard for AAS users. It treats the BP and has some slight PPAR-delta activity for lipids.
Re: Cardiovascular Impact
Posted: Sun Sep 01, 2024 2:30 pm
by MedellinMuscle
It’s the concentric remodeling that’s dangerous. Aerobic work (LISS) can help induce eccentric remodeling to counter the "thickening" of the heart walls.
Re: mTOR Pathway
Posted: Sun Sep 01, 2024 2:47 pm
by Peterdyday
I’ve noticed better recovery with 5g leucine per meal.
Re: Cardiovascular Impact
Posted: Sun Sep 01, 2024 4:10 pm
by SlavPower
Does anyone here donate blood regularly to keep hematocrit down? I find it helps with the "heavy heart" feeling on high doses.
Re: Cardio Impact
Posted: Sun Sep 01, 2024 4:20 pm
by SlavPower
Hematocrit management is key too. Thick blood puts massive strain on the heart during heavy lifting.
Re: mTOR Pathway
Posted: Sun Sep 01, 2024 4:32 pm
by SlavPower
Is there an upper limit where it becomes redundant?