mTOR Pathway: Leucine Threshold vs. Total Protein
mTOR Pathway
Starting a deep dive into leucine thresholds...
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Herbertysnilm
- Posts: 2
- Joined: Mon Jan 12, 2026 12:44 am
Re: Cardio Impact
Left Ventricular Hypertrophy (LVH) is almost inevitable for long term heavy users. The question is management of blood pressure.
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Herbertysnilm
- Posts: 2
- Joined: Mon Jan 12, 2026 12:44 am
Re: Cardiovascular Impact
The heart is a muscle. If you give it orals and heavy gear for a decade, Left Ventricular Hypertrophy (LVH) is a statistical certainty.
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MedellinMuscle
- Posts: 13
- Joined: Mon Dec 08, 2025 3:25 am
Re: mTOR Pathway
The 3g threshold is often cited, but bodyweight matters.
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MedellinMuscle
- Posts: 13
- Joined: Mon Dec 08, 2025 3:25 am
Re: Cardio Impact
Telmisartan is the gold standard for AAS users. It treats the BP and has some slight PPAR-delta activity for lipids.
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MedellinMuscle
- Posts: 13
- Joined: Mon Dec 08, 2025 3:25 am
Re: Cardiovascular Impact
It’s the concentric remodeling that’s dangerous. Aerobic work (LISS) can help induce eccentric remodeling to counter the "thickening" of the heart walls.
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Peterdyday
- Posts: 1
- Joined: Sat Jan 03, 2026 7:16 pm
Re: mTOR Pathway
I’ve noticed better recovery with 5g leucine per meal.
Re: Cardiovascular Impact
Does anyone here donate blood regularly to keep hematocrit down? I find it helps with the "heavy heart" feeling on high doses.
Re: Cardio Impact
Hematocrit management is key too. Thick blood puts massive strain on the heart during heavy lifting.
Re: mTOR Pathway
Is there an upper limit where it becomes redundant?
