Problem: I finished my AI protocol 4 days ago and now my nipples are sensitive again.
Context:
* Was using Arimidex 0.5mg EOD.
* Stopped cold turkey after cycle ended.
The Mechanics:
Is this just a standard rebound because Arimidex doesn't destroy the enzyme? Should I have tapered off?
Estrogen Rebound After Stopping AI
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CoachIronwell
- Posts: 62
- Joined: Mon Dec 08, 2025 3:29 am
Re: Rebound Management
Yes, Arimidex is notorious for this. The enzymes are just "busy" while on the drug, then they all release at once.
Re: Rebound Management
Switch to Aromasin next time. It’s a suicide inhibitor, so no rebound.
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CoachIronwell
- Posts: 62
- Joined: Mon Dec 08, 2025 3:29 am
Re: Rebound Management
Should I start a low dose of Nolva to block the receptors for now?
Re: Rebound Management
Definitely. 20mg Nolva until the sensitivity dies down.
